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Changes in blood sugar control If you have diabetes, you might notice: More stable blood sugar readings Lower fasting blood sugar levels Potentially a drop in your A1C beyond what semaglutide achieved For someone with an A1C of about 7% on semaglutide, tirzepatide might bring it closer to your target goal
Others require 2 to 3 weeks before noticing meaningful changes
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And gastrointestinal effects are the most frequently reported, including: Nausea (especially in the first few weeks) Vomiting Diarrhea Constipation Stomach pain Heartburn Most people find these side effects improve as their body adjusts to the medication, typically within four to eight weeks